close

Вход

Забыли?

вход по аккаунту

код для вставкиСкачать
A
Supplemental Figure 1
B
Normal Breast Epithelium
TRAB/2F
TRAB/2O
M.W.
i
ii
TRAB/2F
TRAB/2O
+
+
105
84
50
35
29
18
iv
iii
C Frequency of Elafin-Positive Cells
None=0
<1% =1
1-10% =2
10-33% =3
33-66% =4
66-100% =5
D Staining Intensity of Elafin-Positive Cells
Negative=0
Low=1
Medium=2
High=3
-
-
GFs
A
Supplemental Figure 2
TCGA Breast
Luminal B
Normal
-2
2
Log2-Median Centered
Normal
Luminal B
Luminal A
HER2+
Basal-like
Luminal A
Log2-mean centered values
Basal
p<0.0001
HER2
p<0.0001
PAM50
B
p=0.0015
PI3 (Elafin)
TCGA Breast
Univariate analysis ovarian cancer (n=213) Supplemental Table 1
A
Factors
Age at diagnosis, year
Mean
Median (range)
Histological Type
Serous
Endometroid
Clear Cell
Transitional Cell
Malignant Mixed Müllerian
Undifferentiated
Others
FIGO stage
I/II
III/IV
Grade
Low
High
Ascites Level
No
Yes
Unknown
Response to treatment
No
Yes
Unknown
Serum CA 125 level
<500 U/mL
>500 U/mL
Unknown
Elafin
Negative (n=171)
Positive (n=42)
57.5
58 (20-83)
59.6
63 (27-87)
125 (73.1)
19 (11.1)
8 (4.7)
4 (2.3)
7 (4.0)
7 (4.0)
1 (0.6)
32 (76.2)
2 (4.8)
1 (2.4)
2 (4.8)
1 (2.4)
2 (4.8)
2 (4.8)
p-value
0.09
0.7
0.006
33 (19.3)
138 (80.8)
3 (7.2)
39 (92.8)
0.5
15 (8.8)
156 (91.2)
2 (4.8)
40 (95.2)
18 (15)
102 (85)
51
1 (2.5)
39 (97.5)
2
0.05
0.02
24 (15)
136 (85)
11
12 (30.8)
27 (69.2)
3
0.018
43 (45.3)
52 (54.7)
76
6 (20)
24 (80)
12
B
Multivariate Cox Proportional Hazards Analysis of Clinicopathologic Variables’
Influence on Ovarian Cancer Disease-Specific Survival (DSS) in whole cohort (n=213)
Factor
HR
Se
P
95% CI
Referent
3.43
0.93
2.77
0.15
1.39
0.21
1.21
0.04
0.002
0.7
0.02
<0.0001
1.55
0.60
1.18
0.09
Stage
I/II
III/IV
Elafin Positive
Ascites
Response to treatment
1/--страниц
Пожаловаться на содержимое документа