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Essential Training Package for HPV Vaccine Introduction
Module 3
HPV vaccine eligibility and
contraindications
CervarixTM
Learning objectives
 At the end of the module, you will have learned to:
– Describe the recommended immunization schedule for
CervarixTM
– Describe when a girl is eligible for HPV vaccine and
when she is not eligible
– Describe the absolute contraindications for vaccination
 Duration
– 60’
2 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
Key issues
What is the schedule and dosage
1 for CervarixTM?
How do you determine a girl’s
2 eligibility for HPV vaccine?
3 What to do when…?
4 What are the precautions and
contraindications?
3 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
What is the schedule for CervarixTM,
vaccine administration?
Example schedule
Dose 1
Dose 2
Dose 3
Interval
of 1 month
Interval of 6 months
4 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
Who should get HPV vaccine?

5 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015

Are there contraindications to HPV
vaccination?
 HPV vaccine is not recommended for:
SEVERE
FEBRILE
ILLNESS
A minor infection such as a cold is not a contraindication
6 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
What should you do in this scenario?
The girl is pregnant when she
returns for third dose
of HPV vaccine.
7 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
What should you do in this scenario?
The girl is immunocompromised
due to HIV/AIDS.
8 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
What should you do in this scenario?
The girl came in to an
immunization session. She is 4
months late for the second
dose.
9 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
Key messages
 CervarixTM is a 3 dose schedule, administered within 6
months
- between 1st and 2nd dose: interval of 1 month
- between 1st and 3rd dose: interval of 6 months
 Girls between 9 and 13 years old are eligible for HPV
vaccination
 Contrindications for HPV vaccination are:
- Allergy after a previous vaccine dose, or to a component of the
vaccine
- Pregnancy
- Severe febrile illness
10 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
End of module
Thank you
for your attention!
11 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
References
 Comprehensive Cervical Cancer Control. A guide to essential
practice (C4 GEP). WHO 2013
 HPV vaccine introduction into national immunization
programmes: Information for programme managers and
health workers. WHO 2013
 CervarixTM package inserts. GlaxoSmithKline 2009
12 | HPV vaccine eligibility and contraindications,
Module 3 CervarixTM| 25 February 2015
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