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Computational Biology Research Group
Department of Microbiology, University of Washington, Seattle
http://www.compbio.washington.edu/
Instructions:
The genetic code is the set of rules by which information encoded in
genetic material (DNA or RNA sequences) is translated into proteins
(amino acid sequences) by living cells. Specifically, the code defines a
mapping between trinucleotide sequences called codons and amino
acids.
For a given codon (3 nucleotide sequence) to find the amino acid coded
1.Start with the first nucleotide center blue circle
2.Follow the second nucleotide from red circle
3.Follow the third nucleotide from green circle
AAA codes for the amino acid Lysine (K)
Example: GGU GAA AAU GAG ACU AUU UGU
G
E
N
E
T
I
C
--- --- --- --- --- --- ---
CRACK THE FOLLOWING CODES
ACC AGG GCU AAU AGU UUA GCG ACU AUC ... AAC
T
R
A
N
S
L
A
T
I
O
N
1. --- --- --- --- --- --- --- --- --- --- ---
m-RNA base Codons
... AUA ... AUU AAC UUC ... CGG AUG GCA ACG AUU UGU UCA
B
I
O
I
N
F
O
R
M
A
T
I
C
S
2. --- --- --- --- --- --- --- --- --- --- --- --- --- --UUU ... UUG GAC AUA AAU GGG
F
O
L
D
I
N
G
3. --- --- --- --- --- --- ---
CCU AGG AUC ... AAC
P
R
I
O
N
4. --- --- --- --- ---
Instructions:
Amino acids are the structural units that make up proteins. They all have
different atomic composition and thus structures. Using the table on the
right decipher the following protein hieroglyphs.
P A S I F I C
P
A S I F I C
___________________
S C I E N C E
___________________
C
H A R L E S
______________________
F R A N C I S
______________________
R I C H A R D
______________________
For online version visit:
C E N T E R
_______________
D A R W I N
_________________
C R I C K
________________
F E Y N M A N
____________________
http://protinfo.compbio.washington.edu/prostring/
Alanine
Ala
A
Arginine
Arg
R
Asparagine
Asn
N
Aspartic acid
Asp
D
Cysteine
Cys
C
Glutamic acid
Glu
E
Glutamine
Gln
Q
Glycine
Gly
G
Histidine
His
H
Isoleucine
Ile
I
Leucine
Leu
L
Lysine
Lys
K
Methionine
Met
M
Phenylalanine
Phe
F
Proline
Pro
P
Serine
Ser
S
Threonine
Thr
T
Tryptophan
Trp
W
Tyrosine
Tyr
Y
Valine
Val
V
Computational Biology Research Group
Instructions:
Department of Microbiology, University of Washington, Seattle
http://www.compbio.washington.edu/
Write your name in both sections A and B and translate it into the “Genetic Code” and the “Protein Hieroglyph”.
When you finish let us check it…
____________________________________________
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